EJMCR. 2017; 1(January 2017): 48-51

Bilateral adrenal hemorrhage in APLS (anti-phospholipid syndrome) patient on Novel Anticoagulant: a case report

Authors: Ebtisam A Bakhsh, Reem A Alkhathami, Shazia Mukaddam, Ohoud Alarfaj.

ABSTRACT

Background: Antiphospholipid syndrome is a prothrombotic state characterized by the existence of persistent antiphospholipid antibodies. The key sequence of events is focal microthrombosis and post-infarction hemorrhage in the adrenal glands. Use of anticoagulant therapy is often used as a prevention and treatment among patients. Case presentation: We describe a case of 40 year old female who visited Emergency Room with complain of severe right upper quadrant pain for two days associated with nausea and vomiting. Initial laboratory investigations of blood, liver, and renal functions were normal. CT scan of abdomen revealed diffused enlargement of the right adrenal gland and showed relatively less enhancement indicating hemorrhage at the right side which later developed bilateral during admission. A day after admission, platelet count was 60,000 accompanied with worsened abdominal pain lead to diagnosis of catastrophic Anti-phospholipid syndrome (APLS). Conclusion: APS may lead to a variety of clinical manifestations due to venous and/or arterial thrombosis, so prescribing novel anticoagulants for patients with the APS is selective, and multiple factors are needed to be considered for a successful treatment.

Keywords:
Antiphospholipid syndrome, adrenal hemorrhage, case report, anticoagulant therapy, bilateral hemorrhage, adrenal insufficiency


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Bilateral adrenal hemorrhage in APLS (anti-phospholipid syndrome) patient on Novel Anticoagulant: a case report


Authors
Ebtisam A Bakhsh

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Reem A Alkhathami

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Shazia Mukaddam

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Ohoud Alarfaj

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Correspondence to:
. Princess Nourah Bint Abdulrahman University, Faculty of Medicine, Clinical Sciences Department, Riyadh, Saudi Arabia. ;

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Pubmed Style

Ebtisam A Bakhsh, Reem A Alkhathami, Shazia Mukaddam, Ohoud Alarfaj. Bilateral adrenal hemorrhage in APLS (anti-phospholipid syndrome) patient on Novel Anticoagulant: a case report. EJMCR. 2017; 1(January 2017): 48-51. doi:10.24911/ejmcr/1/12


Web Style

Ebtisam A Bakhsh, Reem A Alkhathami, Shazia Mukaddam, Ohoud Alarfaj. Bilateral adrenal hemorrhage in APLS (anti-phospholipid syndrome) patient on Novel Anticoagulant: a case report. http://www.ejmcr.com/?mno=267659 [Access: November 21, 2018]. doi:10.24911/ejmcr/1/12


AMA (American Medical Association) Style

Ebtisam A Bakhsh, Reem A Alkhathami, Shazia Mukaddam, Ohoud Alarfaj. Bilateral adrenal hemorrhage in APLS (anti-phospholipid syndrome) patient on Novel Anticoagulant: a case report. EJMCR. 2017; 1(January 2017): 48-51. doi:10.24911/ejmcr/1/12


Vancouver/ICMJE Style

Ebtisam A Bakhsh, Reem A Alkhathami, Shazia Mukaddam, Ohoud Alarfaj. Bilateral adrenal hemorrhage in APLS (anti-phospholipid syndrome) patient on Novel Anticoagulant: a case report. EJMCR. (2017), [cited November 21, 2018]; 1(January 2017): 48-51. doi:10.24911/ejmcr/1/12


Harvard Style

Ebtisam A Bakhsh, Reem A Alkhathami, Shazia Mukaddam, Ohoud Alarfaj (2017) Bilateral adrenal hemorrhage in APLS (anti-phospholipid syndrome) patient on Novel Anticoagulant: a case report. EJMCR, 1 (January 2017), 48-51. doi:10.24911/ejmcr/1/12


Turabian Style

Ebtisam A Bakhsh, Reem A Alkhathami, Shazia Mukaddam, Ohoud Alarfaj. 2017. Bilateral adrenal hemorrhage in APLS (anti-phospholipid syndrome) patient on Novel Anticoagulant: a case report. European Journal of Medical Case Reports, 1 (January 2017), 48-51. doi:10.24911/ejmcr/1/12


Chicago Style

Ebtisam A Bakhsh, Reem A Alkhathami, Shazia Mukaddam, Ohoud Alarfaj. "Bilateral adrenal hemorrhage in APLS (anti-phospholipid syndrome) patient on Novel Anticoagulant: a case report." European Journal of Medical Case Reports 1 (2017), 48-51. doi:10.24911/ejmcr/1/12


MLA (The Modern Language Association) Style

Ebtisam A Bakhsh, Reem A Alkhathami, Shazia Mukaddam, Ohoud Alarfaj. "Bilateral adrenal hemorrhage in APLS (anti-phospholipid syndrome) patient on Novel Anticoagulant: a case report." European Journal of Medical Case Reports 1.January 2017 (2017), 48-51. Print. doi:10.24911/ejmcr/1/12


APA (American Psychological Association) Style

Ebtisam A Bakhsh, Reem A Alkhathami, Shazia Mukaddam, Ohoud Alarfaj (2017) Bilateral adrenal hemorrhage in APLS (anti-phospholipid syndrome) patient on Novel Anticoagulant: a case report. European Journal of Medical Case Reports, 1 (January 2017), 48-51. doi:10.24911/ejmcr/1/12


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