Systemic Lupus Erythematosus associated refractory pancytopenia responding only to intravenous immunoglobulins
Authors: Tahir Iqbal, Wajahat Sultan Baig, Saamia Arshad, Sara Altaf Awan
Background: We, here, describe the case of Systemic Lupus Erythematosus (SLE) with pancytopenia, refractory to steroids immunosuppressive therapy, and plasmapharesis that ultimately responded to intravenous immunoglobulins (IVIG). To the best of our knowledge, very few cases of this type have been reported in literature. Case presentation: A 40-year-old female presented with complaints of hematemesis, hematochezia, gum bleed, epistaxis, menorrhagia, and fever. After careful examination and investigation she was diagnosed with SLE associated with pancytopenia refractory to conventional means of treatment. Pancytopenia responds normally to steroids and immunosuppressive agents in these patients however our patient responded only to IVIG. Conclusion: This case report highlights the fact that early use of Intravenous immunoglobulins in patients of SLE with severe and refractory pancytopenia can prevent morbidity and mortality..
Keywords: SLE, pancytopenia, intravenous immunoglobulins, case report.
Authors
Tahir Iqbal
Department of Medicine, Shifa College of Medicine (Shifa Tameer e Millat University), Consultant Medical Specialist, Shifa International Hospital, Islamabad, Pakistan
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Correspondence to:
Wajahat Sultan Baig, Senior Registrar, Department of Medicine, Shifa College of Medicine(Shifa Tameer e Millat University), Islamabad, Pakistan wajahat_sultan@yahoo.com
Publication history:
Received 26 Aug 2019
Accepted 23 Apr 2020
Published online 05 May 2020
Published in print 24 May 2020
Iqbal T, Baig WS, Arshad S, Awan SA. Systemic Lupus Erythematosus associated refractory pancytopenia responding only to intravenous immunoglobulins. EJMCR. 2020; 4(4): 123-125. doi:
10.24911/ejmcr/173-1566719209
Iqbal T, Baig WS, Arshad S, Awan SA. Systemic Lupus Erythematosus associated refractory pancytopenia responding only to intravenous immunoglobulins. https://www.ejmcr.com/?mno=62630 [Access: May 15, 2024]. doi:
10.24911/ejmcr/173-1566719209
Iqbal T, Baig WS, Arshad S, Awan SA. Systemic Lupus Erythematosus associated refractory pancytopenia responding only to intravenous immunoglobulins. EJMCR. 2020; 4(4): 123-125. doi:
10.24911/ejmcr/173-1566719209
Iqbal T, Baig WS, Arshad S, Awan SA. Systemic Lupus Erythematosus associated refractory pancytopenia responding only to intravenous immunoglobulins. EJMCR. (2020), [cited May 15, 2024]; 4(4): 123-125. doi:
10.24911/ejmcr/173-1566719209
Iqbal, T., Baig, . W. S., Arshad, . S. & Awan, . S. A. (2020) Systemic Lupus Erythematosus associated refractory pancytopenia responding only to intravenous immunoglobulins. EJMCR, 4 (4), 123-125. doi:
10.24911/ejmcr/173-1566719209
Iqbal, Tahir, Wajahat Sultan Baig, Saamia Arshad, and Sara Altaf Awan. 2020. Systemic Lupus Erythematosus associated refractory pancytopenia responding only to intravenous immunoglobulins. European Journal of Medical Case Reports, 4 (4), 123-125. doi:
10.24911/ejmcr/173-1566719209
Iqbal, Tahir, Wajahat Sultan Baig, Saamia Arshad, and Sara Altaf Awan. "Systemic Lupus Erythematosus associated refractory pancytopenia responding only to intravenous immunoglobulins." European Journal of Medical Case Reports 4 (2020), 123-125. doi:
10.24911/ejmcr/173-1566719209
Iqbal, Tahir, Wajahat Sultan Baig, Saamia Arshad, and Sara Altaf Awan. "Systemic Lupus Erythematosus associated refractory pancytopenia responding only to intravenous immunoglobulins." European Journal of Medical Case Reports 4.4 (2020), 123-125. Print. doi:
10.24911/ejmcr/173-1566719209
Iqbal, T., Baig, . W. S., Arshad, . S. & Awan, . S. A. (2020) Systemic Lupus Erythematosus associated refractory pancytopenia responding only to intravenous immunoglobulins. European Journal of Medical Case Reports, 4 (4), 123-125. doi:
10.24911/ejmcr/173-1566719209