Giant inflammatory myofibroblastic tumor of oral cavity: a case report and literature review
Authors: Demet Etit, Ardan Vergili, Muberra Konur, Mustafa Koray Balcı
Background: Inflammatory myofibroblastic tumor is an infrequent lesion that is seen in the lungs, abdomen, skin, soft tissue, genital system, and mediastinum. It is rare in the oral cavity. Case presentation: A 58-year-old woman presented with a mass in the left buccal mucosa. An extensive surgical intervention was performed. On gross examination, the mass was 9.5 x 8 x 3.5 cm in size. Microscopically, the tumor included spindle-shaped myofibroblast-like cells intermingling chronic inflammatory cells. Differential diagnosis of inflammatory myofibroblastic tumor is extensive and includes benign and malignant spindle cell tumors, such as cranial fasciitis, solitary fibrous tumor, fibrosarcoma, and rhabdomyosarcoma. Conclusion: Inflammatory myofibroblastic tumors are classified as tumors of intermediate biological potential due to a tendency of local recurrence and low risk of distance metastasis. We found it appropriate to submit this case because of its rarity and rapid growth; also, it is the largest size oral cavity location inflammatory myofibroblastic tumor that has been reported so far.
Keywords: Inflammatory myofibroblastic tumor, inflammatory pseudotumor, oral cavity, ALK-1, case report
Authors
Demet Etit
Department of Pathology Istanbul Aydin University, Istanbul, Turkey, Department of Pathology, IKCU Ataturk Training and Research, Hospital, Izmir, Turkey
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Correspondence to:
Demet Etit, Department of Pathology Istanbul Aydin University, Istanbul, Turkey, Department of Pathology, IKCU Ataturk Training and Research, Hospital, Izmir, Turkey demetetit@yahoo.com
Publication history:
Received 06 Mar 2021
Revised 17 Jan 2022
Accepted 18 Mar 2022
Published online 10 Apr 2022
Published in print 20 Apr 2022
Etit D, Vergili A, Konur M, Balcı MK. Giant inflammatory myofibroblastic tumor of oral cavity: a case report and literature review. EJMCR. 2022; 6(3): 43-47. doi:
10.24911/ejmcr/173-1614786678
Etit D, Vergili A, Konur M, Balcı MK. Giant inflammatory myofibroblastic tumor of oral cavity: a case report and literature review. https://www.ejmcr.com/?mno=60797 [Access: April 24, 2024]. doi:
10.24911/ejmcr/173-1614786678
Etit D, Vergili A, Konur M, Balcı MK. Giant inflammatory myofibroblastic tumor of oral cavity: a case report and literature review. EJMCR. 2022; 6(3): 43-47. doi:
10.24911/ejmcr/173-1614786678
Etit D, Vergili A, Konur M, Balcı MK. Giant inflammatory myofibroblastic tumor of oral cavity: a case report and literature review. EJMCR. (2022), [cited April 24, 2024]; 6(3): 43-47. doi:
10.24911/ejmcr/173-1614786678
Etit, D., Vergili, . A., Konur, . M. & Balcı, . M. K. (2022) Giant inflammatory myofibroblastic tumor of oral cavity: a case report and literature review. EJMCR, 6 (3), 43-47. doi:
10.24911/ejmcr/173-1614786678
Etit, Demet, Ardan Vergili, Muberra Konur, and Mustafa Koray Balcı. 2022. Giant inflammatory myofibroblastic tumor of oral cavity: a case report and literature review. European Journal of Medical Case Reports, 6 (3), 43-47. doi:
10.24911/ejmcr/173-1614786678
Etit, Demet, Ardan Vergili, Muberra Konur, and Mustafa Koray Balcı. "Giant inflammatory myofibroblastic tumor of oral cavity: a case report and literature review." European Journal of Medical Case Reports 6 (2022), 43-47. doi:
10.24911/ejmcr/173-1614786678
Etit, Demet, Ardan Vergili, Muberra Konur, and Mustafa Koray Balcı. "Giant inflammatory myofibroblastic tumor of oral cavity: a case report and literature review." European Journal of Medical Case Reports 6.3 (2022), 43-47. Print. doi:
10.24911/ejmcr/173-1614786678
Etit, D., Vergili, . A., Konur, . M. & Balcı, . M. K. (2022) Giant inflammatory myofibroblastic tumor of oral cavity: a case report and literature review. European Journal of Medical Case Reports, 6 (3), 43-47. doi:
10.24911/ejmcr/173-1614786678