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Case Report

Published: Apr 28, 2025 | DOI: 10.24911/ejmcr.9-1676

A Rare Case of Papillary Thyroid Carcinoma with Neurological Presentation - A Case Report

Authors: Joao Diogo Moreira Faustino , Eva Brandao , Raquel Vieira , Claudia Rosado

Article Info

Authors

Joao Diogo Moreira Faustino

Department of Internal Medicine, Unidade Local de Saúde da Região de Aveiro, Aveiro, Portugal

Eva Brandao

Neurology, Unidade Local de Saúde Entre Douro e Vouga, Santa Maria da Feira, Portugal

Raquel Vieira

Department of Internal Medicine, Unidade Local de Saúde da Região de Aveiro, Aveiro, Portugal

Claudia Rosado

Department of Internal Medicine, Unidade Local de Saúde da Região de Aveiro, Aveiro, Portugal

Publication History

Received: January 23, 2025

Accepted: April 08, 2025

Published: April 28, 2025

Abstract

Background: Longitudinal extensive transverse myelitis, which designates inflammation of the spinal cord in more than 3 vertical vertebral segments, is a rare presentation of paraneoplastic syndrome, being more common in lung or lymphoproliferative neoplasms. Before diagnosing myelitis of paraneoplastic etiology, the aim is to exclude inflammatory, metabolic, infectious and ischemic/traumatic causes.

Case Report: We present a 62-year-old man observed in the emergency department for low back pain that had lasted 2 weeks, paresthesia of the lower limbs and severe inability to walk. He also referred sphincter anesthesia in the previous 3 days. Several examinations were carried out and the dorso-lumbar magnetic resonance imaging highlighted findings of longitudinal extensive transverse myelitis from D5-D6 to the conus medullaris. The etiological study showed papillary thyroid carcinoma as a condition for this paraneoplastic syndrome. After thyroidectomy, the patient progressively recovered from the deficits presented.

Conclusions: The clinical and imaging diagnosis of myelitis is not difficult, however, finding the underlying etiology can be challenging. A whole set of laboratory and imaging tests are necessary to confirm the cause and direct treatment with the intention of potentially reversing the neurological condition.

Keywords: Longitudinal transverse myelitis; Paraneoplastic Syndrome; Papillary Thyroid Carcinoma; Nuclear Medicine

Pubmed Style

Joao Diogo Moreira Faustino, Eva Brandao, Raquel Vieira, Claudia Rosado. A Rare Case of Papillary Thyroid Carcinoma with Neurological Presentation - A Case Report. EJMCR. 2025; 28 (April 2025): -. doi:10.24911/ejmcr.9-1676

Web Style

Joao Diogo Moreira Faustino, Eva Brandao, Raquel Vieira, Claudia Rosado. A Rare Case of Papillary Thyroid Carcinoma with Neurological Presentation - A Case Report. https://www.ejmcr.com/articles/1676 [Access: May 02, 2025]. doi:10.24911/ejmcr.9-1676

AMA (American Medical Association) Style

Vancouver/ICMJE Style

Joao Diogo Moreira Faustino, Eva Brandao, Raquel Vieira, Claudia Rosado. A Rare Case of Papillary Thyroid Carcinoma with Neurological Presentation - A Case Report. EJMCR. (2025), [cited May 02, 2025]; 28 (April 2025): -. doi:10.24911/ejmcr.9-1676

Harvard Style

Joao Diogo Moreira Faustino, Eva Brandao, Raquel Vieira, Claudia Rosado (2025) A Rare Case of Papillary Thyroid Carcinoma with Neurological Presentation - A Case Report. EJMCR, 28 (April 2025): -. doi:10.24911/ejmcr.9-1676

Chicago Style

Joao Diogo Moreira Faustino, Eva Brandao, Raquel Vieira, Claudia Rosado. "A Rare Case of Papillary Thyroid Carcinoma with Neurological Presentation - A Case Report." 28 (2025), -. doi:10.24911/ejmcr.9-1676

MLA (The Modern Language Association) Style

Joao Diogo Moreira Faustino, Eva Brandao, Raquel Vieira, Claudia Rosado. "A Rare Case of Papillary Thyroid Carcinoma with Neurological Presentation - A Case Report." 28.April 2025 (2025), -. Print. doi:10.24911/ejmcr.9-1676

APA (American Psychological Association) Style

Joao Diogo Moreira Faustino, Eva Brandao, Raquel Vieira, Claudia Rosado (2025) A Rare Case of Papillary Thyroid Carcinoma with Neurological Presentation - A Case Report. , 28 (April 2025), -. doi:10.24911/ejmcr.9-1676