Case Report

Published: Apr 04, 2026 | DOI: 10.24911/ejmcr.9-2417

Rheumatoid Arthritis Diagnostic Pitfalls: Dont Overlook Large Joint Efussion


Authors: Perdana Aditya Rahman ORCID logo , Michelle Anabel ORCID logo , ms. Dyto Prasetya Buwana , Farah Diyah Anjani


Abstract

Background Rheumatoid arthritis (RA) is a systemic autoimmune disease that commonly presents of inflammatory symmetric polyarthritis in small joints and may also have extra-articular involvement. Early diagnosis and treatment within the first 3 months are important to reduce progression and deformities. In some cases, large joint involvement may also present or initially present in RA, which may lead to lower suspicion of RA at the initial visit and results in delayed diagnosis. Case Presentation Here we present a case of female, 55 years old with knee joint pain and effusion, which initially thought to be osteoarthritis. The patient had inflammatory arthritis features including morning stiffness, pain worsened at rest, and arthritis also involving hands. Yet, the patient was confirmed as having rheumatoid arthritis based on clinical, serological, and radiological features. In the detailed evaluation of knee radiographic examination, bone erosions were identified at a second look. Conclusion Inflammatory arthritis involving large joints requires detailed history taking of other joint involvement, serologic evaluation and also thorough radiographic interpretation, thus diagnosis of rheumatoid arthritis involving large joint can be established properly.


Keywords: Knee joint, Joint Efussion, Joint Disease, Rheumatoid Arthritis, Osteoarthritis, Case Report



Pubmed Style

Perdana Aditya Rahman, Michelle Anabel, ms. Dyto Prasetya Buwana, Farah Diyah Anjani. Rheumatoid Arthritis Diagnostic Pitfalls: Dont Overlook Large Joint Efussion. EJMCR. 2026; 04 (April 2026): -. doi:10.24911/ejmcr.9-2417

Publication History

Received: December 09, 2025

Revised: February 17, 2026

Accepted: February 18, 2026

Published: April 04, 2026


Authors

Perdana Aditya Rahman

Rheumatology-Immunology Division, Department of Internal Medicine, Faculty of Medicine, Brawijaya University, Malang

ORCID logo ORCID

Michelle Anabel

Brawijaya University, Faculty of Medicine

ORCID logo ORCID

ms. Dyto Prasetya Buwana

Brawijaya University, Faculty of Medicine

Farah Diyah Anjani

Brawijaya University, Faculty of Medicine